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r prognosticate for patients arriving alive to hospital with CCD. Level of evidence III.Background Although age and coagulopathy are well-known predictors of poor outcome after traumatic brain injury (TBI), the interaction effect of these two predictors remains unclear. Objectives We assessed age-related differences in the impact of coagulopathy on the outcome following isolated TBI. Methods We conducted a retrospective observational study in two tertiary emergency critical care medical centers in Japan from 2013 to 2018. A total of 1036
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