https://www.selleckchem.com/pr....oducts/baf312-siponi
05). Compared with calcium oxalate treatment alone, the above deleterious changes were further significantly confirmed by GdCl but were reversed by NPS-2390. However, urine calcium excretion was decreased after ethylene glycol treatment but was significantly reduced by NPS 2390 and increased by GdCl ( .05). The results suggest that CaSR might play significant roles in the induction of nephrolithiasis in rats by regulating reactive oxygen species (ROS) and PS ectropion and the composition of urine, OPN, KIM-1, and ERK expr
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