https://www.selleckchem.com/products/PLX-4032.html
We respond to the comments of Ma et al. and clarify the rationale behind our methodology and why it is suitable for our work.A diastereoselective three-component reaction of diazo compounds with alcohols and pyrazolinone ketimines by utilizing rhodium(ii) catalysis via interception of transient oxonium ylides is reported. The reaction provides an efficient approach for the facile construction of polyfunctionalized pyrazolone derivatives bearing two contiguous quaternary stereocenters in good yields with high regioselectivities and exce
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