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In this review, sequential stages of the development of negative disorders doctrine are presented beginning from first description of negative symptoms (Aretaeus of Cappadocia - AD I-II) and the first deficit classification (including two polar types congenital and acquired dementia by J.-E. Esquirol) to indigenous Russian (I.M. Balinsky, I.P. Merzheevsky, S.S. Korsakov, V.P. Serbsky and others) and foreign (B. Morel, H. Schüle, K. Kahlbaum, E. Hecker) studies of the middle 19th - beginning of 20th century. Special attention in this review
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