https://www.selleckchem.com/products/E7080.html
The search for more biocompatible alternatives to Gd 3+ -based MRI agents, and the interest in 52 Mn for PET imaging call for ligands that form inert Mn 2+ chelates. Given the labile nature of Mn 2+ , high inertness is challenging to achieve. The strongly preorganized structure of the 2,4-pyridyl-disubstituted bispidol ligand L 1 endows its Mn 2+ complex with exceptional kinetic inertness. Indeed, MnL 1 did not show any dissociation for 140 days in the presence of 50 eq. of Zn 2+ (37°C, pH 6), while recently reported potential MRI agents
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