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We followed up the patient 2 months and 6 months after operation. At present, the patient recovered well, had no headache, and her spirit was significantly better than that before operation. Cranial neuroendocrine cancer has diverse clinical manifestations. CgA, Syn, Ki-67, CD56, and ACTH are important reference indicators for the diagnosis of neuroendocrine cancer. Neuroendoscopic transsphenoidal approach is a safe and effective surgical method. Cranial neuroendocrine cancer has diverse clinical manifestations. CgA, Syn, Ki-67, CD56, and
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