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02 (95% CI 0.99, 1.06), 1.18 (95% CI 0.94, 1.47) and 1.05 (95% CI 0.83, 1.34) for those ever exposing to shift work, respectively. Compared with daytime workers or those never exposing to night work, the pooled relative risks for all-cause, cardiovascular and cancer mortality were 1.06 (95% CI 1.03, 1.08), 1.15 (95% CI 1.03, 1.29) and 1.04 (95% CI 1.00, 1.08) for those ever exposing to night work, respectively. Moderate to high level of heterogeneity across the studies was detected. Publication bias was not detected. Night work may be a
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