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Elevated POU5F1 was involving poor OS, DFS, RFS, and DSS in several cancers. POU5F1 ended up being confirmed as a completely independent danger factor for LIHC and correlated with cyst occurrence, stage, and intrusion depth. The mixture of POU5F1 and AFP in plasma was with a high diagnostic validity (AUC=0.902, p.001). Especially, the degree of POU5F1 was correlated with infiltrating amounts of B cells, T cells, dendritic cells, and monocytes in LIHC. GSEA indicated that
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