https://www.selleckchem.com/pr....oducts/congo-red.htm
Upregulation of SIRT1 expression was observed in the optic nerve after SRT2104 treatment. CONCLUSION The SIRT1 activator SRT2104 exerts axonal protection in TNF-induced optic nerve degeneration. This effect may be associated with upregulated autophagic status in the optic nerve.PURPOSE To evaluate neurodegeneration in patients with type 2 Diabetes Mellitus (DM2) without diabetic retinopathy, and to assess the possible role of chronic systemic ischaemia and disease duration in retinal changes. STUDY DESIGN Observational cross sectional
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