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Besides, it was also found that miR-204 mimic strongly decreased CXCR4 expression and miR-204 inhibitor increased CXCR4 expression. Furthermore, luciferase assay results demonstrated that CXCR4 was the direct target of miR-204. Conversely to miR-204 effect, knockdown of CXCR4 showed an inhibitory effect on NPC cell progression. Mechanistic investigations revealed that miR-204 regulated NF-κB signaling via CXCR4. Conclusion Taken together, our findings suggested that miR-204 regulated NPC progression by targeting CXCR4 through NF-κB signa
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