https://www.selleckchem.com/pr....oducts/ldn-212854.ht
Subsequently, the freeze-drying methodology was validated in an industrial setting, yielding a CPC634 freeze-dried cake with a moisture content of less than 0.1wt%. It was found that trehalose-cryoprotected CPC634 could be rapidly reconstituted in less than 5min at room temperature. Critical quality attributes such as size, morphology, drug retention, and release kinetics of trehalose-cryoprotected freeze-dried CPC634 upon reconstitution were identical to those of non-freeze-dried CPC634. Our findings provide proof-of-concept for the
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