https://www.selleckchem.com/pr....oducts/ch4987655.htm
Long-read phasing has been used for reconstructing diploid genomes, improving variant calling, and resolving microbial strains in metagenomics. However, the phasing blocks of existing methods are broken by large Structural Variations (SVs), and the efficiency is unsatisfactory for population-scale phasing. This paper presents a novel algorithm, LongPhase, which can simultaneously phase single nucleotide polymorphisms (SNPs) and SVs of a human genome in 10-20 minutes, 10x faster than the state-of-the-art WhatsHap, HapCUT2 and Margin. I
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