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lic-assisted therapies and could, in the long-term, open new treatment avenues in several domains. Forthcoming studies shouldassess toxicity/safety and clinical outcomes of patients receiving Amazonian tobacco-based treatment. To our knowledge, this is the first study employing a transdisciplinary clinical approach to examine therapeutic applications of tobacco by an Amazonian tabaquero. Our findings significantly contribute to the growing research literature on Amazonian medicine and emergent psychedelic-assisted therapies and could,
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