https://www.selleckchem.com/pr....oducts/pd-166866.htm
ned release of Losartan. Sepsis has well-documented inflammatory effects on cardiovascular and blood cells. This study is designed to investigate potential anti-inflammatory effects of metformin on cardiac and blood cells 12 and 24 h following cecal ligation and puncture (CLP)-induced sepsis. For the purpose of this study, 36 male Wistar rats were divided into six groups two groups underwent CLP, two groups underwent CLP and received metformin, and two groups only received sham operations. 12 h later, 18 rats (half of rats in each of
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