https://www.selleckchem.com/pr....oducts/ITF2357(Givin
In addition, by using three different C. elegans PD models, HT and OLE were shown i) to enhance locomotion in worms suffering from α-synuclein-expression in muscles or rotenone exposure, ii) to reduce α-synuclein accumulation in muscles cells, and iii) to prevent neurodegeneration in α-synuclein-containing dopaminergic neurons. Hormesis, antioxidative capacities and an activity-boost of the proteasome phase II detoxifying enzymes are discussed as potential underlying causes for these beneficial effects. Further biologi
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