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25 mm), time (45 min) and temperature (45°C). The maximum experimental yield of diosgenin (1.204% dry weight) was observed close to the predicted value (1.202% dry weight) on the basis of the chosen optimal extraction factors. The developed mathematical model fitted well with experimental data for diosgenin extraction. Experimental validation revealed that a well trained ANN model has superior performance compared to a RSM model. Experimental validation revealed that a well trained ANN model has superior performance compared to a RSM mode
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