https://www.selleckchem.com/products/thz531.html
Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)-mediated AKI. The miRNA cluster (encoding , , , , , and ) regulates angiogenesis in multiple settings, but no definitive role in renal endothelium during AKI pathogenesis has been established. Antibodies bound to magnetic beads were utilized to selectively enrich for renal endothelial cells from mice. Endothelial-specific knockout ( ) mice were generated and given renal IRI. Mice were monitored for the development of AKI using serum chemistries
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