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Recommendations for applied researchers are made based on the results. An empirical example using data from the ATLAS drug prevention intervention study is presented to illustrate these results. Limitations and future directions are discussed. Peri-implant osteolysis is one of the major complications related to total ankle replacement. The aim of this study was to investigate the short- to midterm incidence of peri-implant osteolysis using computed tomography (CT) as imaging method for the Trabecular Metal Total Ankle (TMTA) implant rep
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