https://highcontentscreenings.....com/index.php/a-long
A well-characterised function of TPX2 may be the activation, stabilisation and spindle localisation of this Aurora-A kinase. High levels of TPX2 are reported in tumours therefore the effects of its overexpression have now been investigated in cancer tumors cell outlines, while small is known in non-transformed cells. Right here we studied TPX2 overexpression in hTERT RPE-1 cells, making use of either the entire size TPX2 or a truncated form not able to bind Aurora-A, to spot impacts being depend
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