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The mutation of the mouse klotho gene leads to a syndrome resembling aging including calcification of the aorta. To examine the relationship between serum soluble klotho levels and abdominal aorta calcification (AAC) in subjects aged 60-79years. The National Health and Nutrition Examination Survey data were analyzed using logistic regression models to examine the independent association between soluble klotho tertile levels and the Kauppila AAC-24 score. A total of 1042 participants with a median klotho level of 796pg/ml comprised the
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