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The overall outcomes revealed a statistical need for vitamin D therapy in patients with COPD on forced expiratory volume in 1 second (FEV1) (SMD 1.21, 95% CI 0.76-1.66, P less then 0.01), FEV1/FVC (SMD 1.07, 95% CI 0.56-1.58, P less then 0.01), Exacerbations (SMD 0.39, 95% CI 0.23-0.64, P less then 0.01), Sputum volume (SMD -6.02, 95% CI -8.25 to 3.79, P less then 0.01), 6-minute walk distance (6MWD) (MD 8.82, 95% CI 1.67-15.98, P=0.02) and COPD evaluation test (CAT) score (SMD -1.19, 95% CI -1.74 to 0.6
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