https://www.selleckchem.com/pr....oducts/molidustat-(b
Furthermore, a strong anti-clonogenic effect of compound 4i on lung cancer cells was observed. The flow cytometric analysis investigation reveals that compound 4i arrests the A549 cancer cell lines at the G0/G1 phase of the cell cycle. Molecular docking were also performed on 4i, 4j, and erlotinib to predict the binding mode towards the EGFR kinase (PDB code 1M17) and the compounds have displayed similar interactions and compared with erlotinib. CONCLUSION Overall, these findings could suggest that the compound 4i would
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