https://www.selleckchem.com/products/AT7519.html
Overexpression of cryab, hspb2 and tbx5 rescued the cardiac oedema phenotype of mog1 KO zebrafish. Telemetry electrocardiogram monitoring showed QRS and QTc prolongation and a reduced heart rate in mog1 knockout zebrafish, which was associated with reduced scn1b expression. Moreover, mog1 knockout resulted in abnormal cardiac looping during embryogenesis because of the reduced expression of nkx2.5, gata4 and hand2. Our data identified an important molecular determinant for cardiac hypertrophy and heart failure, and rhythm maintenance of
Beğen
Yorum Yap
Paylaş
