https://www.selleckchem.com/pr....oducts/pacap-1-38.ht
In MDS, mutations of genes, such as NRAS and FLT3, designated as type-1 genes, are significantly associated with leukemic evolution. On the other hand, mutations in type-2 genes, including RUNX1 and GATA2, are related to progression from low risk MDS to high risk MDS.Leukocytes that lack HLA allelic expression (HLA-LLs) caused by a copy-number-neutral loss of heterozygosity in the short arm of chromosome 6 (6pLOH) and somatic mutations in HLA class I genes are commonly identified in patients with acquired aplastic anemia (AA), althou
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