https://www.selleckchem.com/pr....oducts/gsk591-epz015
n, we reveal that elevated Mgll levels in cultured adult NPCs from both 3xTg-AD and CbpS436A animal models are responsible for their NPC neuronal differentiation deficits. Conclusion Our findings set the stage for development of a clinical protocol where Mgll would serve as a biomarker in early stages of AD to identify potential metformin-responsive AD patients to restore their neurogenesis and spatial memory.Fluorescence microscopy is widely used for high content screening in 2D cell cultures and 3D models. In parti
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