https://www.selleckchem.com/ALK.html
And high LIPH expression was significantly correlated with KRAS activation and SMAD4 inactivation. Besides, LIPH expression was involved in various biological pathways such as negative regulation of cell-cell adhesion, actin cytoskeleton, EMT, angiogenesis, and signaling by MST1. And LIPH overexpression caused high infiltration of TAMs, Treg cells, and Th2/Th1, but reduced the infiltration of CD8 T cells and Th1 cells. Our findings demonstrated that LIPH correlated with immune suppression or evasion and may function as a novel unfavorable prognostic
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