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To evaluate the relationship between occupational and environmental exposure to pesticides and Parkinson disease in a region of intense agribusiness activity in the state of Mato Grosso/Brazil. Case-control study carried out in a referral hospital for chronic neurodegenerative diseases. Non-conditional logistic regression analyses were performed. Having performed direct management of pesticides in the workplace (odds ratio [OR] 3.43; 95% confidence interval [CI] 1.55 to 7.28), having a family history of Parkinson (OR 3.42; 95% CI 1.61
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