https://www.selleckchem.com/pr....oducts/litronesib.ht
The inhibitory effect of D and L-polynucleotides of a given length (40-50n) on the catalytic activity of DNA polymerase β isolated from chromatin cells of acute myeloid leukemia HL-60 was evaluated. The synthesized L enantiomer was found to have a higher inhibitory activity than the synthesized and isolated D enantiomers of polynucleotides. The work also proposes a biophysical model that describes this effect.Antimicrobial peptides (AMPs) have been appointed as a possible alternative to traditional antibiotics in face of pathogens in
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