https://www.selleckchem.com/pr....oducts/PD-0325901.ht
Heparin resistance (HR), defined as a decrease in heparin responsiveness, can result in adverse events with prolonged duration of surgery. Although some clinical risk factors have been suggested, the relationship with the surgical diagnosis is unclear. The aim of present study was to elucidate the clinical predictors of HR including the surgical diagnosis. This retrospective cohort study determined the incidence of HR (defined as activated clotting time [ACT] 400 seconds after 250-350 IU/kg of heparin administration) and heparin
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