https://www.selleckchem.com/pr....oducts/pamapimod-r-1
The type 3 adenylyl cyclase (AC3) enzyme is involved in the synthesis of cyclic adenosine monophosphate (cAMP). It is primarily expressed in the central nervous system (CNS) and plays a crucial role in neurogenesis and neural dendritic arborization. However, the AC3's functional role in the gastrointestinal tract remains ambiguous. AC3 expression in enteric tissue of AC3 mice was investigated using immunohistochemistry and RT-PCR. AC3 knock-out mice (AC3 ) were used to examine the effect of AC3 on the enteric nervous
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