https://gdc-0152antagonist.com..../intrastromal-as-opp
Right here, we found that DesK-the transmembrane histidine kinase-also responds to pH and examined the mechanism of pH sensing. We propose that a helix linking the transmembrane region aided by the cytoplasmic catalytic domain is tangled up in pH sensing. This helix contains a few glutamate, lysine, and arginine residues At natural pH, the linker forms an alpha helix this is certainly stabilized by hydrogen bonds into the i, i + 4 registe
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