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es best practices for use of the tracer as an imaging biomarker. 18 F-FES PET could enhance breast cancer diagnosis and staging as well as aid in therapy selection for patients with metastatic disease. Tissue sampling limitations, intrapatient heterogeneity, and temporal changes in molecular markers make it likely that 18 F-FES PET will complement existing assays when clinically available in the near future. © AlphaMed Press 2020.Caffeine is the most widely used psychoactive substance in the world and is known to disrupt healthy sleep. However, very few stu
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