https://www.selleckchem.com/pr....oducts/SB-743921.htm
023). Viral integration type was dependent on HPV genotype (p 0.0001); HPV18 and HPV45 being always integrated. High HPV copy number was associated with longer PFS (p = 0.011). This is to our knowledge the first study assessing the prognostic value of HPV integration in a prospectively annotated CC cohort, which detects a hotspot of HPV integration at MACROD2; involved in impaired PARP1 activity and chromosome instability. This is to our knowledge the first study assessing the prognostic value of HPV integration in a prospectivel
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