https://www.selleckchem.com/pr....oducts/Cyclopamine.h
In phase 1, in those without ILA, a 5% increase in emphysema was associated with a reduction in FVC (-110 cc, 95% confidence interval [CI] -121, -100; P0.0001) however, in those with ILA it was not (-11cc, 95% CI -53,31; P=0.59). In contrast, there was no interaction between ILA and emphysema on total lung capacity (TLC) nor on diffusing capacity of carbon monoxide (DLCO). The presence of ILA attenuates the reduction in FVC associated with emphysema. The presence of ILA attenuates the reduction in FVC associated with emphysema.T
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