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The good upshot of the present case shows deciding on this process for patients with RASopathies and brain tumors with hyperactivated MTOR signaling.Philadelphia chromosome (Ph) outcomes from a translocation involving the breakpoint cluster region (BCR) gene on chromosome 9 and ABL proto-oncogene 1 (ABL1) gene on chromosome 22. The fusion gene, BCR-ABL1, is a constitutively active tyrosine kinase which encourages development of leukemia. According to the breakpoint site in the BCR gene, dif