https://www.selleckchem.com/pr....oducts/stat-in-1.htm
Comparable changes in LVEF (fulacimstat 3.5% ± 5.4%, placebo 4.0% ± 5.0%, P = .69), LVEDVI (fulacimstat 7.3 ± 13.3 mL/m2, placebo 5.1 ± 18.9 mL/m2, P = .54), and LVESVI (fulacimstat 2.3 ± 11.2 mL/m2, placebo 0.6 ± 14.8 mL/m2, P = .56) were observed in both treatment arms. CONCLUSION Fulacimstat was safe and well tolerated in patients with left-ventricular dysfunction (LVD) after first STEMI but had no effect on cardiac remodeling. BACKGROUND An amassing body of evidence exists to support an association between the use of immune checkp