https://www.selleckchem.com/pr....oducts/acss2-inhibit
39months; = 0.0496). In myeloma cell line JJN-3, stable overexpression of by lentivirus transduction resulted in reduced cell migration ( = 0.0001) but not impacting cell death or proliferation. This is the first report of tumor-specific methylation-mediated silencing of in myeloma, which is likely an early event in myelomagenesis with adverse impact on overall survival. Moreover, is a tumor suppressor lncRNA by inhibiting myeloma cell migration, hence implicated in myeloma plasma cell homing, metastasis and disease progression.
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