https://www.selleckchem.com/products/r428.html
Interestingly, MEKi-induced STAT activation and interferon-responsive protein expression are abrogated with ErbB-family inhibitor co-treatment in MMTV-Neu cells, suggesting ErbB receptor signaling dependence, but not in basal-like cell lines. Importantly, analysis of basal-like breast cancer patient samples exhibited an inverse relationship between STAT1 and Ras/MAPK activation signatures. These findings suggest that MAPK signaling and STAT activation are inversely related in both mouse and human mammary tumors. This work also supports fur
Beğen
Yorum Yap
Paylaş
