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To examine the effects of laser therapy on rheumatoid arthritis. A search of controlled trials was conducted in different medical electronic databases. The primary outcome was immediate pain relief after treatment. Secondary outcomes were level of functional disability, morning stiffness duration, and 3-month follow-up for pain. Ten trials met the inclusion criteria. Rheumatoid arthritis treatment with laser therapy significantly improved immediate pain relief [standardized mean difference (SMD), -0.839; 95% confidence interval (CI), -1
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