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7%), surgical interventions (32.0%) and biologic agents (15.4%). Logistic regression analysis revealed that the most important determinants of disease severity were male sex (OR=2.21) and involvement of the genitals (OR=3.39) and inguinal region (OR = 2.25). More severe disease was associated with comorbidity, longer disease duration, longer diagnosis delay and a higher number of smoking pack-years. Our nationwide cohort study found demographic and clinical variation in HS, which may help broaden the understanding of HS and factors associ
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