https://www.selleckchem.com/products/LBH-589.html
BACKGROUND Dementia is a growing public health concern with an estimated prevalence of 50 million people worldwide. Alzheimer's disease (AD) and vascular and frontotemporal dementias (VaD, FTD), share many clinical, genetical, and pathological features making the diagnosis difficult. METHODS In this study, we compared the transcriptome from the frontal cortex of patients with AD, VaD, and FTD to identify dysregulated pathways. RESULTS Upregulated genes in AD were enriched in adherens and tight junctions, mitogen-activated protein kinase
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