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It comprises several forms with a highly variegated etiology, primarily united by motor, balance, and speech impairments and, in the muscle amount, by cerebellar atrophy and Purkinje cells deterioration. This is exactly why, the contribution of astrocytes to this condition was mainly over looked in past times. However, within the last few few decades, developing evidences tend to be pointing to cerebellar astrocytes as essential players not just
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