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Better understanding of these irAEs will improve its safety and expand its use in those with underlying autoimmune disease.In recent years the blood proteome has been increasingly researched for biomarkers for early detection of colorectal cancer (CRC). Blood samples from screening studies are often subject to preanalytical variability and repeated freeze-thaw cycles. We aimed to assess the correlation of repeat measurements of 27 candidate protein markers for CRC screening taken three years and multiple freeze-thaw cycles apart. The conc
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