https://www.selleckchem.com/pr....oducts/z-vad(oh)-fmk
Higher childhood body mass index (BMI) has been associated with an increased risk of multiple sclerosis (MS). To evaluate whether childhood BMI has a causal influence on MS, and whether this putative effect is independent from early adult obesity and pubertal timing. We performed Mendelian randomization (MR) using summary genetic data on 14,802 MS cases and 26,703 controls. Large-scale genome-wide association studies provided estimates for BMI in childhood ( = 47,541) and adulthood ( = 322,154). In multivariable MR, we examined
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