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We read with interest the Letter from Bastos et al, on KIDNEY PAIRED DONATION IN BRAZIL - A SINGLE CENTER PERSPECTIVE. Using a designed study the authors showed, mathematically, how Kidney Paired Donation (KPD) could increase Living Donor Kidney Transplant (LDKT) in a single center in Brazil, and by extrapolation, in South America.1.This article tells the story of hormesis from its conceptual and experimental origins, its dismissal by the scientific and medical communities in the first half of the 20th century, and its rediscovery over
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