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This paper illustrates the development of a miniaturized and precise analytical tool for biomonitoring of honey bee exposure to insecticides. This is the first work describing an analytical method for determination of very low concentrations of a wide range of insecticides in maize guttation fluid. Seed treatment with systemic insecticides or their foliar application causes the accumulation of compounds in the guttation liquid, which consists of excess water and compounds removed by plants and is a source of water for bees. A micro-QuEChER
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