https://www.selleckchem.com/
Brain insulin resistance is an important hallmark of age-related conditions, including type 2 diabetes (T2D) and dementia. This systematic review summarized effects of cerebral blood flow (CBF) responses to intranasal insulin to assess brain insulin sensitivity in healthy and diseased populations. We also explored relationships between changes in brain insulin sensitivity and cognitive performance. A systemic literature search (PROSPERO CRD4202230977 identified 58 randomized, placebo-controlled trials (RCTs) that investigated effects of intranasal insulin
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