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Finding the Best Medication For ADHD The most commonly prescribed medication for ADHD is stimulants. Amphetamines and methylphenidates are among the most commonly prescribed stimulants. Short-acting stimulants start working in under an hour and need to be taken several times a day. Long-acting stimulants last for up to 16 hour and are taken once a day. Your doctor may prescribe antidepressants or other kinds of drugs "off-label" to treat ADHD symptoms. These medications are approved to treat disorders such as anxiety or depression. Stimula
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