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The gastric antral biopsy samples with H. pylori vacA s1m2 genotype infection showed a weak correlation with ZAK gene overexpression (p .1). ZAK gene expression was higher in GAECs of gastritis cancer than in gastric adenocarcinoma, indicating the protective effect of ZAK against gastric cancer (p .005). Reducing ZAKgene expression shows the negative correlations with H. pylori infection and gastric adenocarcinoma. ZAK gene expression was higher in GAECs of gastritis cancer than in gastric adenocarcinoma, indicating the protect
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