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0001). The Liver fibrosis score APRI and FIB-4, were higher in the coinfected group compared with HBV monoinfected group (0.67 vs 0.25, p = 0.0085; 3.48 vs 0.98, p = 0.0026), respectively. The cytokine levels of IL-17, Fas-L, TNF -α, IL-10, IL-2and Granzyme B were also measured and compared among the study groups. Our data suggest that HIV probably influences the immune activation of CD4+ and CD8+ T cells, and this may play a significant role in accelerating the disease outcome among HIV/HBV coinfected individuals. Our data suggest that
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